Protein Labeling Reagents
Biotium MUC2(MLP/842), CF488A conjugate, 0.1mg/mL
Recognizes a single glycoprotein of 520 kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium.MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other
![eMolecules BP Fluor 488 Picolyl Azide | Broadpharm |736.690 | C30H24N8O11S2 | 95.000 | Nc1ccc2c(-c3ccc(cc3C(O)=O)C(=O)NCCC(=O)Nc3ccc(CN=[N+]=[N-])nc3)c3ccc(=N)c(c3oc2c1S(O)(=O)=O)S(O)(=O)=O | 25mg | 599128620](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183671.JPG-250.jpg)
eMolecules BP Fluor 488 Picolyl Azide | Broadpharm |736.690 | C30H24N8O11S2 | 95.000 | Nc1ccc2c(-c3ccc(cc3C(O)=O)C(=O)NCCC(=O)Nc3ccc(CN=[N+]=[N-])nc3)c3ccc(=N)c(c3oc2c1S(O)(=O)=O)S(O)(=O)=O | 25mg | 599128620
BP Fluor 488 Picolyl Azide | Broadpharm |736.690 | C30H24N8O11S2 | 95.000 | Nc1ccc2c(-c3ccc(cc3C(O)=O)C(=O)NCCC(=O)Nc3ccc(CN=[N+]=[N-])nc3)c3ccc(=N)c(c3oc2c1S(O)(=O)=O)S(O)(=O)=O | 25mg | 599128620
Biotium HCG-beta(hCGb/459), CF568 conjugate, 0.1mg/mL
This MAb reacts with a protein of 22 kDa, identified as β sub-unit of HCG. It does not cross react with the α sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.Primary antibodies are available purified, or with a selection of fluoresce
Biotium CD106 / VCAM1(1.4C3), CF568 conjugate, 0.1mg/mL
CD106 (also known as vascular cell adhesion molecule-1, or VCAM-1) is a member of the Ig superfamily of adhesion molecules. It is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte beta-1 integrin VLA-4 and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
eMolecules BP Fluor 488 Hydroxylamine TEA salt | Broadpharm |606.580 | C24H22N4O11S2 | 90.000 | NOCCCNC(=O)c1ccc(c(c1)C(O)=O)-c1c2ccc(N)c(c2oc2c(c(=N)ccc12)S(O)(=O)=O)S(O)(=O)=O | 25mg | 599128629
BP Fluor 488 Hydroxylamine TEA salt | Broadpharm |606.580 | C24H22N4O11S2 | 90.000 | NOCCCNC(=O)c1ccc(c(c1)C(O)=O)-c1c2ccc(N)c(c2oc2c(c(=N)ccc12)S(O)(=O)=O)S(O)(=O)=O | 25mg | 599128629
Biotium CD45RB(BRA-11G), CF568 conjugate, 0.1mg/mL
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for
Biotium CDw78(DF1588), CF568 conjugate, 0.1mg/mL
This antibody reacts with a carbohydrate determinant, identified as CDw78 (Workshop V; Code CDw78.2). Epitope recognized by this MAb and Leu21 is the same. It is present on some immature and some peripheral blood B cells, and some B cell lines. Its expression is increased after B-cell activation in vitro. CDw78 is also found on tissue macrophages and on epithelial cells, but not on T cells, NK cells, monocytes, granulocytes and myeloid tissues. It appears that CDw78 is a determinant on a major histocompatibility complex (MHC) class II subpopulation.
(=O)=O)c4ccc(cc4C3(C)C)S([O-])(=O)=O)=C2c2ccc(CCCCC(=O)NCCC(=O)N3Cc4ccccc4C#Cc4ccccc34)cc2)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O | 1mg | 795361773](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502464570.JPG-250.jpg)
eMolecules 2714419-16-4 | Tetra-sulfo-Cy7 DBCO | Broadpharm1259.530 | C65H70N4O14S4 | 0.000 | CC1(C)\C(=C/C=C2\CCCC(\C=C\C3=[N+](CCCS(O)(=O)=O)c4ccc(cc4C3(C)C)S([O-])(=O)=O)=C2c2ccc(CCCCC(=O)NCCC(=O)N3Cc4ccccc4C#Cc4ccccc34)cc2)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O | 1mg | 795361773
Tetra-sulfo-Cy7 DBCO | Broadpharm | 2714419-16-41259.530 | C65H70N4O14S4 | 0.000 | CC1(C)\C(=C/C=C2\CCCC(\C=C\C3=[N+](CCCS(O)(=O)=O)c4ccc(cc4C3(C)C)S([O-])(=O)=O)=C2c2ccc(CCCCC(=O)NCCC(=O)N3Cc4ccccc4C#Cc4ccccc34)cc2)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O | 1mg | 795361773
Meso Scale Discovery V-PLEX Human IL-17A/F Kit
The V-PLEX Human IL-17A/F Kit is a multiplex immunoassay that allows for the simultaneous measurement of human interleukin 17A (IL-17A) and interleukin 17F (IL-17F) in cell culture supernatants serum and plasma This assay utilizes electrochemiluminescence (ECL) technology on the MSD platform for high sensitivity and broad dynamic range The kit includes a plate coated with capture antibodies detection antibodies calibrators and controls needed to quantitatively determine IL-17A and IL-17F concentrations This multiplex assay allows efficient quantification of both analytes from a single small sample volume
Biotium CF405L Tyramide
CF dye tyramide conjugates can be used for tyramide signal amplification (TSA), which is an enzyme-mediated detection method that uses horseradish peroxidase (HRP) to generate high-density labeling of a target protein or nucleic acid in situ. CF dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. 405 nm-excitable green fluorescent CF405L dye has excitation/emission at 395/545 nm.Also see Biotium's CF Dye Tyramide Amplification Kits.
Bachem 6-Carboxy-fluorescein
6-Carboxy-fluorescein, 3301-79-9, C21H12O7, Mr 376.32, 500mg. 6-FAM, 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)-terephthalic acid. Widely used green-fluorescent labeling dye.
